Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Subcellular localization of the human papillomavirus 16 E7 oncoprotein in CaSki cells and its detection in cervical adenocarcinoma and adenocarcinoma in situ

26 Oct 2010

Abstract excerpt

E7 is the major oncoprotein of high-risk human papillomaviruses (HPV) which causes cervical cancer. To date E7 oncoproteins have not been investigated in cervical adenocarcinoma. In this study we generated a rabbit monoclonal anti-HPV-16 E7 antibody, RabMab42-3, which recognizes a conformational epitope in the E7 carboxy-terminal zinc-finger resulting in a strong increase in the sensitivity for the detection of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cervical Cancer and HPV Research
Share to Immunotherapy and Immune Responses
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20970819
DOI: 10.1016/j.virol.2010.09.024

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Subcellular localization of the human papillomavirus 16 E7 oncoprotein in CaSki cells and its detection in cervical adenocarcinoma and adenocarcinoma in situPMID 20970819Read ↗

E6 and E7 Oncoproteins: Potential Targets of Cervical CancerSemantic proximity Read ↗

Molecular mechanisms of cervical carcinogenesis by high‐risk human papillomaviruses: novel functions of E6 and E7 oncoproteinsSemantic proximity Read ↗

Preferential nuclear localization of the human papillomavirus type 16 E6 oncoprotein in cervical carcinoma cellsSemantic proximity Read ↗

Molecular biology of cervical cancer and its precursorsSemantic proximity Read ↗

The Role of HPV E6 and E7 Oncoproteins in HPV-associated Cervical CarcinogenesisSemantic proximity Read ↗

The Subcellular Localisation of the Human Papillomavirus (HPV) 16 E7 Protein in Cervical Cancer Cells and Its Perturbation by RNA AptamersSemantic proximity Read ↗

AIB1 is a novel target of the high‐risk HPV E6 protein and a biomarker of cervical cancer progressionSemantic proximity Read ↗

Association of the human papillomavirus type 16 E7 oncoprotein with the 600-kDa retinoblastoma protein-associated factor, p600Semantic proximity Read ↗

RbAp48 is a critical mediator controlling the transforming activity of human papillomavirus type 16 in cervical cancer.Semantic proximity Read ↗

KAT8 facilitates the proliferation of cancer cells through enhancing E7 function in HPV-associated cervical cancerSemantic proximity Read ↗

Critical roles for non-pRb targets of human papillomavirus type 16 E7 in cervical carcinogenesis.Semantic proximity Read ↗

JAK/STAT Signaling and Cervical Cancer: From the Cell Surface to the NucleusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.