Article
RbAp48 is a critical mediator controlling the transforming activity of human papillomavirus type 16 in cervical cancer.
The Journal of biological chemistry - 7 Sept 2007
Kong Li, Yu Xiu-Ping, Bai Xiao-Hui, Zhang Wei-Fang, Zhang Yan, Zhao Wei-Ming, Jia Ji-Hui, Tang Wei, Zhou Ya-Bin, Liu Chuan-ju
Abstract excerpt
Although human papillomavirus (HPV) infections are the primary cause of cervical cancer, the molecular mechanism by which HPV induces cervical cancer remains largely unclear. We used two-dimensional electrophoresis with mass spectrometry to study protein expression profiling between HPV16-positive cervical mucosa epithelial H8 cells and cervical cancer Caski cells to identify 18 differentially expressed proteins....
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