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Article

Synaptic dysfunction in genetic models of Parkinson's disease: a role for autophagy?

Neurobiology of disease - 1 Jul 2011

Plowey Edward D, Chu Charleen T

Abstract excerpt

The past decade in Parkinson's disease (PD) research has been punctuated by numerous advances in understanding genetic factors that contribute to the disease. Common to most of the genetic models of Parkinsonian neurodegeneration are pathologic mechanisms of mitochondrial dysfunction, secretory vesicle dysfunction and oxidative stress that likely trigger common cell death mechanisms. Whereas presynaptic function...

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Identifiers

PMID: 20969957
DOI: 10.1016/j.nbd.2010.10.011
PMCID: PMC3049988

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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