Article
The pobA gene of Burkholderia cenocepacia encodes a group I Sfp-type phosphopantetheinyltransferase required for biosynthesis of the siderophores ornibactin and pyochelin.
Microbiology (Reading, England) - 1 Feb 2011
Asghar Atif H, Shastri Sravanthi, Dave Emma, Wowk Irena, Agnoli Kirsty, Cook Anne M, Thomas Mark S
Abstract excerpt
The opportunistic pathogen Burkholderia cenocepacia produces the siderophores ornibactin and pyochelin under iron-restricted conditions. Biosynthesis of both siderophores requires the involvement of non-ribosomal peptide synthetases (NRPSs). Using a transposon containing the lacZ reporter gene, two B. cenocepacia mutants were isolated which were deficient in siderophore production. Mutant IW10 was shown to...
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