Article
Importance of the ornibactin and pyochelin siderophore transport systems in Burkholderia cenocepacia lung infections.
Infection and immunity - 1 May 2004
Visser M B, Majumdar S, Hani E, Sokol P A
Abstract excerpt
Previously, orbA, the gene encoding the outer membrane receptor for ferric-ornibactin, was identified in Burkholderia cenocepacia K56-2, a strain which produces ornibactin, salicylic acid, and negligible amounts of pyochelin. A K56-2 orbA mutant was less virulent than the parent strain in a rat agar bead infection model. In this study, an orbA mutant of B. cenocepacia Pc715j which produces pyochelin in addition...
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