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Article

Nitric oxide stimulates human sperm motility via activation of the cyclic GMP/protein kinase G signaling pathway

21 Oct 2010

Abstract excerpt

Nitric oxide (NO), a modulator of several physiological processes, is involved in different human sperm functions. We have investigated whether NO may stimulate the motility of human spermatozoa via activation of the soluble guanylate cyclase (sGC)/cGMP pathway. Sperm samples obtained by masturbation from 70 normozoospermic patients were processed by the swim-up technique. The kinetic parameters of the motile...

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PMID: 20965947
DOI: 10.1530/rep-10-0151

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