Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Correlation between intracellular cAMP content, kinematic parameters and hyperactivation of human spermatozoa after incubation with pentoxifylline

1 Apr 1998

Abstract excerpt

Various compounds have been used in the attempt to improve sperm motility, including pentoxifylline (PF), a methylxanthine derivative. It has been postulated that PF, being a phosphodiesterase inhibitor, increases sperm kinematic parameters and the number of spermatozoa exhibiting hyperactivated motility by raising the intracellular content of cAMP, a molecule involved in the generation of sperm energy. However,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Assisted Reproductive Technology and Twin Pregnancy
Share to Reproductive Health and Technologies
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9619547
DOI: 10.1093/humrep/13.4.911

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Correlation between intracellular cAMP content, kinematic parameters and hyperactivation of human spermatozoa after incubation with pentoxifyllinePMID 9619547Read ↗

Pentoxifylline stimulates various sperm motion parameters and cervical mucus penetrability in patients with asthenozoospermiaSemantic proximity Read ↗

Shedding light on the role of cAMP in mammalian sperm physiologySemantic proximity Read ↗

Pentoxifylline: actions and applications in assisted reproductionSemantic proximity Read ↗

Hyperactivation of mammalian spermatozoa: function and regulationSemantic proximity Read ↗

Extracellular cAMP activates molecular signalling pathways associated with sperm capacitation in bovinesSemantic proximity Read ↗

Structure-based redesigning of pentoxifylline analogs against selective phosphodiesterases to modulate sperm functional competence for assisted reproductive technologiesSemantic proximity Read ↗

Kinematic Changes During the Cryopreservation of Boar SpermatozoaSemantic proximity Read ↗

Enhancement of motility and acrosome reaction in human spermatozoa: differential activation by type-specific phosphodiesterase inhibitorsSemantic proximity Read ↗

Sperm treatment with extracellular ATP increases fertilization rates in in-vitro fertilization for male factor infertilitySemantic proximity Read ↗

Behavioral mechanism of human sperm in thermotaxis: a role for hyperactivationSemantic proximity Read ↗

Behavioral Mechanism during Human Sperm Chemotaxis: Involvement of HyperactivationSemantic proximity Read ↗

Changes of PKA and PDK1 in the principal piece of boar spermatozoa treated with a cell‐permeable cAMP analog to induce flagellar hyperactivationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.