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EFFECTS OF NITRIC OXIDE ON HUMAN SPERMATOZOA ACTIVITY, FERTILIZATION AND MOUSE EMBRYONIC DEVELOPMENT

12 Apr 2004

Abstract excerpt

This study was conducted to investigate the effects of nitric oxide (NO) on human sperm activity, human sperm-oocyte fusion and mouse embryonic development. Results showed that various concentrations of NO synthase blocker, N(omega)-nitro-L-arginine methyl ester, did not affect sperm cell motility at 0, 1, 2 or 4 hr, respectively. In contrast, sodium nitroprusside (SNP) significantly inhibited sperm cell motility...

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PMID: 15204684
DOI: 10.1080/01485010490425494

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