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Article

Phosphatidylinositol 3-kinase inhibition enhances human sperm motility

1 Sept 2001

Abstract excerpt

BACKGROUND: The number of spermatozoa with forward motility after capacitation procedures represents the limiting factor for application of IVF versus intracytoplasmatic sperm injection (ICSI) procedure in cases of oligoasthenozoospermia. The possibility of increasing this number may thus be of help to the patient. A complex array of signalling pathways is involved in the regulation of sperm motility and recent...

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PMID: 11527900
DOI: 10.1093/humrep/16.9.1931

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