Article
Phase I/II study of FOLFIRI in Japanese patients with advanced colorectal cancer.
Japanese journal of clinical oncology - 1 Feb 2011
Yamashita Keishi, Nagashima Fumio, Fujita Ken-ichi, Yamamoto Wataru, Endo Hisashi, Miya Toshimichi, Narabayashi Masaru, Kawara Kaori, Akiyama Yuko, Ando Yuichi, Ando Masahiko, Sasaki Yasutsuna
Abstract excerpt
OBJECTIVE: This phase I/II study determined the recommended dose of FOLFIRI (irinotecan, infusional 5-fluorouracil and leucovorin) for Japanese patients with advanced colorectal cancer, and evaluated safety at the recommended dose in patients without the UDP-glucuronosyltransferase 1A1*28 allele...
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