Article
13915*G DNA polymorphism associated with lactase persistence in Africa interacts with Oct-1.
Human genetics - 1 Jan 2011
Olds Lynne C, Ahn Jong Kun, Sibley Eric
Abstract excerpt
Lactase gene expression declines with aging (lactase non-persistence) in the majority of humans worldwide. Lactase persistence is a heritable autosomal dominant condition and has been strongly correlated with several single nucleotide polymorphisms (SNPs) located ~14-kb upstream (-13907, -13910 and -13915) of the lactase gene in different ethnic populations. In contrast to the -13907*G and -13910*T SNPs, the...
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