Article
In vitro susceptibility of Actinobaculum schaalii to 12 antimicrobial agents and molecular analysis of fluoroquinolone resistance.
The Journal of antimicrobial chemotherapy - 1 Dec 2010
Cattoir Vincent, Varca Alexandre, Greub Gilbert, Prod'hom Guy, Legrand Patrick, Lienhard Reto
Abstract excerpt
OBJECTIVES: To assess the in vitro susceptibility of Actinobaculum schaalii to 12 antimicrobial agents as well as to dissect the genetic basis of fluoroquinolone resistance. METHODS: Forty-eight human clinical isolates of A. schaalii collected in Switzerland and France were studied. Each isolate...
Topics
- Actinomycetaceae
- Actinomycetales Infections
- Amino Acid Sequence
- Anti-Bacterial Agents
- Ciprofloxacin
- DNA Gyrase
- DNA Topoisomerase IV
- Drug Resistance, Bacterial
- Fluoroquinolones
- France
- Humans
- Microbial Sensitivity Tests
- Molecular Sequence Data
- Mutation
- Sequence Analysis, DNA
- Switzerland
- Trimethoprim, Sulfamethoxazole Drug Combination
- Urinary Tract Infections