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Article

Non-invasive prenatal detection of trisomy 21 using tandem single nucleotide polymorphisms.

PloS one - 8 Oct 2010

Ghanta Sujana, Mitchell Michael E, Ames Mary, Hidestrand Mats, Simpson Pippa, Goetsch Mary, Thilly William G, Struble Craig A, Tomita-Mitchell Aoy

Abstract excerpt

BACKGROUND: Screening tests for Trisomy 21 (T21), also known as Down syndrome, are routinely performed for the majority of pregnant women. However, current tests rely on either evaluating non-specific markers, which lead to false negative and false positive results, or on invasive tests, which wh...

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Share to Genomic variations and chromosomal abnormalities
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 20949031
DOI: 10.1371/journal.pone.0013184
PMCID: PMC2951898

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20949031-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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