Article
Increasing genotype-phenotype model determinism: application to bivariate reading/language traits and epistatic interactions in language-impaired families.
Human heredity - 1 Jan 2010
Simmons Tabatha R, Flax Judy F, Azaro Marco A, Hayter Jared E, Justice Laura M, Petrill Stephen A, Bassett Anne S, Tallal Paula, Brzustowicz Linda M, Bartlett Christopher W
Abstract excerpt
While advances in network and pathway analysis have flourished in the era of genome-wide association analysis, understanding the genetic mechanism of individual loci on phenotypes is still readily accomplished using genetic modeling approaches. Here, we demonstrate two novel genotype-phenotype models implemented in a flexible genetic modeling platform. The examples come from analysis of families with specific...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.