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Article

ADAMTS-13 deficiency: can it cause chronic renal failure?

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Feb 2011

Bramham Kate, Hilton Rachel, Horsfield Catherine, McDonald Vickie, Camilleri Raymond, Hunt Beverley J

Abstract excerpt

We describe a case of a 45-year-old woman with progressive chronic kidney disease (CKD), macrocytic anaemia without fragments or thrombocytopaenia, and thrombotic microangiopathy on renal biopsy. 'A disintegrin and metalloprotease, with thrombospondin-1-like domains' (ADAMTS-13) deficiency was detected, and genotyping revealed single-nucleotide polymorphisms known to be associated with reduced ADAMTS-13 secretion...

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Identifiers

PMID: 20947535
DOI: 10.1093/ndt/gfq644

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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