Article
Renal diseases in haemophilic patients: pathogenesis and clinical management.
European journal of haematology - 1 Oct 2013
Esposito Pasquale, Rampino Teresa, Gregorini Marilena, Fasoli Gianluca, Gamba Gabriella, Dal Canton Antonio
Abstract excerpt
Haemophilia A and B are genetic X-linked bleeding disorders, caused by mutations in genes encoding factors VIII and IX, respectively. Clinical manifestations of haemophilia are spontaneous haemorrhage or acute bleeding caused by minor trauma, resulting in severe functional consequences that can culminate in a debilitating arthropathy. Life expectancy and quality of life of patients with haemophilia have...
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