Article
Prospective study of low-dose ristocetin-induced platelet aggregation to identify type 2B von Willebrand disease (VWD) and platelet-type VWD in children.
Thrombosis and haemostasis - 1 Dec 2010
Frontroth Juan Pablo, Hepner Mirta, Sciuccati Gabriela, Feliú Torres Aurora, Pieroni Graciela, Bonduel Mariana
Abstract excerpt
Type 2B von Willebrand disease (VWD2B) and platelet-type von Willebrand disease (PT-VWD) are rare bleeding disorders characterised by an increased ristocetin-induced platelet aggregation (RIPA) at low dose of ristocetin. It was the objective of this study to detect children with VWD2B and PT-VWD using RIPA at low dose of ristocetin (0.5 mg/ml) in the screening evaluation of bleeding disorders, and to analyse the...
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