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Article

Type 2B von Willebrand Disease: A Matter of Plasma Plus Platelet Abnormality.

Seminars in thrombosis and hemostasis - 1 Jul 2016

Castaman Giancarlo, Federici Augusto B

Abstract excerpt

Type 2B von Willebrand disease (VWD2B) is a rare, autosomal-dominant inherited bleeding disorder, characterized by an enhanced ristocetin-induced platelet aggregation in platelet-rich plasma and often with variable degree of thrombocytopenia and loss of high-molecular-weight multimers von Willebrand factor (VWF). All these phenomena are caused by a mutant VWF, normally synthesized and assembled by endothelial...

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Source

Identifiers

PMID: 27148840
DOI: 10.1055/s-0036-1579638

Genes

VWF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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