Article
Type 2B von Willebrand Disease: Early Manifestation as Neonatal Thrombocytopenia.
Hamostaseologie - 1 Dec 2021
Kranzhöfer David, Pavlova Anna, Schneider Hendryk, Franck Peter, Glonnegger Hannah, Büchsel Martin, Yoshimi-Nöllke Ayami, Oldenburg Johannes, Zieger Barbara
Abstract excerpt
Here, we report about a preterm female newborn with a prolonged course of severe thrombocytopenia and hematomas. The family history was positive for von Willebrand disease type 2B (VWD 2B). Diagnosis of VWD 2B was identified analyzing von Willebrand factor (VWF) parameters (VWF:antigen, VWF:activity, VWF multimer analyses) and performing light transmission aggregometry (with half concentration of ristocetin). In...
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