Article
Association between the Thr431Asn polymorphism of the ROCK2 gene and risk of developing metastases of breast cancer.
Oncology research - 1 Jan 2010
Kalender Mehmet E, Demiryürek Seniz, Oztuzcu Serdar, Kizilyer Ayse, Demiryürek Abdullah T, Sevinc Alper, Dikilitas Mustafa, Yildiz Ramazan, Camci Celalettin
Abstract excerpt
The objective of this study was to analyze the genotype distributions and allele frequencies for ROCK2 Thr431Asn and Arg83Lys polymorphisms among breast cancer patients. In this case-control study, 223 patients with breast cancer were recruited and divided into two groups according to metastases (n = 128) and without metastases (n = 95). Genomic DNA from the patients and the control cases (n = 150) was analyzed...
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