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Article

Screening of the DNA mismatch repair genes MLH1, MSH2 and MSH6 in a Greek cohort of Lynch syndrome suspected families.

BMC cancer - 11 Oct 2010

Thodi Georgia, Fostira Florentia, Sandaltzopoulos Raphael, Nasioulas George, Grivas Anastasios, Boukovinas Ioannis, Mylonaki Maria, Panopoulos Christos, Magic Mirjana Brankovic, Fountzilas George, Yannoukakos Drakoulis

Abstract excerpt

BACKGROUND: Germline mutations in the DNA mismatch repair genes predispose to Lynch syndrome, thus conferring a high relative risk of colorectal and endometrial cancer. The MLH1, MSH2 and MSH6 mutational spectrum reported so far involves minor alterations scattered throughout their coding regions...

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Share to Adaptor Proteins, Signal Transducing
Share to Base Pair Mismatch

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colorectal Neoplasms, Hereditary Nonpolyposis

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Source

Open in PubMed Open full text

Identifiers

PMID: 20937110
DOI: 10.1186/1471-2407-10-544
PMCID: PMC2976752

Genes

MLH1
MSH2
MSH6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20937110-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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Screening of the DNA mismatch repair genes MLH1, MSH2 and MSH6 in a Greek cohort of Lynch syndrome suspected families.PMID 20937110Read ↗

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