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Article

Induction of neuronal cell death by paraneoplastic Ma1 antigen

8 Oct 2010

Abstract excerpt

Paraneoplastic Ma1 (PNMA1) is a member of a family of proteins involved in an autoimmune disorder called paraneoplastic neurological syndrome. Although it is widely expressed in brain, nothing is known about the function of PNMA1 in neurons. We find that PNMA1 expression is highest in the perinatal brain, a period during which developmentally regulated neuronal death occurs. PNMA1 expression increases in...

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PMID: 20936693
DOI: 10.1002/jnr.22506

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