Article
Mutations that permit residual CFTR function delay acquisition of multiple respiratory pathogens in CF patients.
Respiratory research - 8 Oct 2010
Green Deanna M, McDougal Kathryn E, Blackman Scott M, Sosnay Patrick R, Henderson Lindsay B, Naughton Kathleen M, Collaco J Michael, Cutting Garry R
Abstract excerpt
BACKGROUND: Lung infection by various organisms is a characteristic feature of cystic fibrosis (CF). CFTR genotype effects acquisition of Pseudomonas aeruginosa (Pa), however the effect on acquisition of other infectious organisms that frequently precede Pa is relatively unknown. Understanding the role of CFTR in the acquisition of organisms first detected in patients may help guide symptomatic and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.