Article
Free copper distinguishes mild cognitive impairment subjects from healthy elderly individuals.
Journal of Alzheimer's disease : JAD - 1 Jan 2011
Squitti Rosanna, Ghidoni Roberta, Scrascia Federica, Benussi Luisa, Panetta Valentina, Pasqualetti Patrizio, Moffa Filomena, Bernardini Silvia, Ventriglia Mariacarla, Binetti Giuliano, Rossini Paolo Maria
Abstract excerpt
In patients affected by Alzheimer's disease (AD), serum copper not bound to ceruloplasmin ('free' copper) appears elevated, slightly but significantly enough to distinguish AD patients from healthy elderly subjects. In this paper we tested the hypothesis that this is also the case for individuals affected by mild cognitive impairment (MCI). A sample of 83 MCI subjects were compared with 100 elderly control...
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