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Human haploid cells differentiated from meiotic competent clonal germ cell lines that originated from embryonic stem cells.

Stem cells and development - 1 Jun 2011

West Franklin D, Mumaw Jennifer L, Gallegos-Cardenas Amalia, Young Amber, Stice Steven L

Abstract excerpt

Early germ-like cells (GLCs) derived from human embryonic stem cells (hESCs) have presented new opportunities to study germ cell differentiation in vitro. However, differentiation conditions that facilitate the formation of haploid cells from the derived GLCs have eluded the field. The inability to propagate GLCs in culture is a further limitation, resulting in inconsistent rederivations of GLCs from hESCs with...

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PMID: 20929355
DOI: 10.1089/scd.2010.0255

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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