Article
A STAT6 gene polymorphism is associated with high infection levels in urinary schistosomiasis.
Genes and immunity - 1 Apr 2008
He H, Isnard A, Kouriba B, Cabantous S, Dessein A, Doumbo O, Chevillard C
Abstract excerpt
Th2-mediated immunity is critical for human defence against schistosome, and susceptibility to infection is controlled by a major genetic locus, mapped on the 5q31-q33 region comprising the genes IL4, IL5 and IL13. We have reported an association between the rs1800925 polymorphism in the IL13 pro...
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