A STAT6 gene polymorphism is associated with high infection levels in urinary schistosomiasis.

doi:10.1038/gene.2008.2

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Article

A STAT6 gene polymorphism is associated with high infection levels in urinary schistosomiasis.

Genes and immunity - 1 Apr 2008

He H, Isnard A, Kouriba B, Cabantous S, Dessein A, Doumbo O, Chevillard C

Abstract excerpt

Th2-mediated immunity is critical for human defence against schistosome, and susceptibility to infection is controlled by a major genetic locus, mapped on the 5q31-q33 region comprising the genes IL4, IL5 and IL13. We have reported an association between the rs1800925 polymorphism in the IL13 promoter and infection levels in a Dogon population (693 subjects in Ségué and 148 in Boul), where Schistosoma haematobium...

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PMID: 18273035
DOI: 10.1038/gene.2008.2

Genes

IL13
STAT6
IL4
IL5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A STAT6 gene polymorphism is associated with high infection levels in urinary schistosomiasis.PMID 18273035Read ↗

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