Article
Proteobactin and a yersiniabactin-related siderophore mediate iron acquisition in Proteus mirabilis.
Molecular microbiology - 1 Oct 2010
Himpsl Stephanie D, Pearson Melanie M, Arewång Carl J, Nusca Tyler D, Sherman David H, Mobley Harry L T
Abstract excerpt
Proteus mirabilis causes complicated urinary tract infections (UTIs). While the urinary tract is an iron-limiting environment, iron acquisition remains poorly characterized for this uropathogen. Microarray analysis of P. mirabilis HI4320 cultured under iron limitation identified 45 significantly upregulated genes (P ≤ 0.05) that represent 21 putative iron-regulated systems. Two gene clusters, PMI0229-0239 and...
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