Article
Differences in exon expression and alternatively spliced genes in blood of multiple sclerosis compared to healthy control subjects.
Journal of neuroimmunology - 1 Jan 2011
Tian Yingfang, Apperson Michelle L, Ander Bradley P, Liu Dazhi, Stomova Boryana S, Jickling Glen C, Enriquez Richelle, Agius Mark A, Sharp Frank R
Abstract excerpt
Using whole genome exon microarrays 120 exons were differentially expressed between medication-free multiple sclerosis (MS) subjects in remission and healthy control subjects (HS) (p<0.001, fold change>|1.2|). These exons differentiated MS from HS using cluster analyses, principal components analyses (PCAs) and cross-validation. In addition, 340 genes (transcripts) were predicted to be alternatively spliced in MS...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
