Article
Genomic large rearrangement screening of BRCA1 and BRCA2 genes in high-risk Turkish breast/ovarian cancer patients by using multiplex ligation-dependent probe amplification assay.
Cancer investigation - 1 Jan 2011
Manguoğlu Esra, Güran Sefik, Yamaç Deniz, Simşek Mehmet, Akdeniz Selime, Colak Taner, Gülkesen Hakan, Lüleci Güven
Abstract excerpt
In this study, MLPA assay was performed for detection of large rearrangements of BRCA1 and BRCA2 genes in 16 familial, 29 early onset, 3 male breast cancer, and 2 bilateral breast/ovarian cancer high risk Turkish index cases. MLPA assay for all exons of both genes and for 1100delC variant of CHEK...
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