Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Screening for large rearrangements of the BRCA2 gene in Spanish families with breast/ovarian cancer.

Breast cancer research and treatment - 1 May 2007

Gutiérrez-Enríquez Sara, de la Hoya Miguel, Martínez-Bouzas Cristina, Sanchez de Abajo Ana, Ramón y Cajal Teresa, Llort Gemma, Blanco Ignacio, Beristain Elena, Díaz-Rubio Eduardo, Alonso Carmen, Tejada María-Isabel, Caldés Trinidad, Diez Orland

Abstract excerpt

Germ-line mutations in BRCA1 and BRCA2 are responsible for about 30-60% of the hereditary breast and ovarian cancer (HBOC). A large number of point mutations have been described in both genes. However, large deletions and duplications that disrupt one or more exons are overlooked by point mutatio...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to Breast Neoplasms, Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosome Deletion

Share to Family Health

Share to Gene Duplication

Share to Genes, BRCA2

Share to Ovarian Neoplasms

Source

Identifiers

PMID: 17063271
DOI: 10.1007/s10549-006-9376-8

Genes

BRCA2
BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17063271-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Screening for large rearrangements of the BRCA2 gene in Spanish families with breast/ovarian cancer.PMID 17063271Read ↗

Identification of a novel BRCA1 large genomic rearrangement in a Spanish breast/ovarian cancer family.Semantic proximity Read ↗

Identification and comprehensive characterization of large genomic rearrangements in the BRCA1 and BRCA2 genes.Semantic proximity Read ↗

Genomic rearrangements at the BRCA1 locus in Spanish families with breast/ovarian cancer.Semantic proximity Read ↗

Genomic rearrangements of the BRCA1 gene in Chilean breast cancer families: an MLPA analysis.Semantic proximity Read ↗

Frequency and distribution of BRCA1/BRCA2 large genomic rearrangements in Turkish population with breast cancer.Semantic proximity Read ↗

Large genomic rearrangements of both BRCA2 and BRCA1 are a feature of the inherited breast/ovarian cancer phenotype in selected families.Semantic proximity Read ↗

Large genomic deletions inactivate the BRCA2 gene in breast cancer families.Semantic proximity Read ↗

Analysis of large deletions in BRCA1, BRCA2 and PALB2 genes in Finnish breast and ovarian cancer families.Semantic proximity Read ↗

Using MLPA for large genomic rearrangements detection in breast cancer predisposition genes.Semantic proximity Read ↗

High occurrence of BRCA1 intragenic rearrangements in hereditary breast and ovarian cancer syndrome in the Czech RepublicSemantic proximity Read ↗

Large BRCA1 and BRCA2 genomic rearrangements in Polish high-risk breast and ovarian cancer families.Semantic proximity Read ↗

Large genomic rearrangements of BRCA1 and BRCA2 among patients referred for genetic analysis in Galicia (NW Spain): delimitation and mechanism of three novel BRCA1 rearrangements.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.