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Article

STK39 is an independent risk factor for male hypertension in Han Chinese.

International journal of cardiology - 26 Jan 2012

Chen Li-Yan, Zhao Wei-Hua, Tian Wen, Guo Jian, Jiang Feng, Jin Li-Juan, Sun Ying-Xian, Chen Kai-Ming, An Li-Li, Li Guo-Dong, Li Qing, Li Yang, Wu Chong, Zhao Ling, Wang Wen-Jing, Zheng Gu-Yan, Li Bing, Li Xue-Qi, Hu Jian, Tian Xiao-Li

Abstract excerpt

BACKGROUND: STK39 interacts with OXSR1 and phosphorylates the sodium-chloride co-transporter (SLC12A3), which plays a critical role in regulating the salt/water balance and blood pressure. Here we tested whether STK39, OXSR1, and SLC12A3 genetically contribute to hypertension in the Han Chinese population and how the SNP to SNP or SNP to other risk factors interacts in the pathogenesis of hypertension. METHODS...

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Source

Identifiers

PMID: 20889219
DOI: 10.1016/j.ijcard.2010.09.007

Genes

STK39
OXSR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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