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Article

Serine/threonine kinase 39 is a candidate gene for primary hypertension especially in women: results from two cohort studies in Swedes.

Journal of hypertension - 1 Mar 2011

Fava Cristiano, Danese Elisa, Montagnana Martina, Sjögren Marketa, Almgren Peter, Engström Gunnar, Nilsson Peter, Hedblad Bo, Guidi Gian C, Minuz Pietro, Melander Olle

Abstract excerpt

BACKGROUND: As recently pinpointed by a genome-wide association study the serine/threonine kinase 39 (STK39) is a candidate gene for hypertension. This kinase is strongly implicated in sodium reabsorption by the kidney through its modulating effect on furosemide-sensitive and thiazide-sensitive channels. The aim of our study was to test the effects of the STK39 rs35929607A>G polymorphism on blood pressure (BP)...

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Source

Identifiers

PMID: 21178783
DOI: 10.1097/HJH.0b013e328342b2c1

Genes

STK39
DBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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