Article
Pharmacogenetic aspects in therapeutic management of subfoveal choroidal neovascularisation: role of factor XIII-A 185 T-allele.
Current drug targets - 1 Feb 2011
Parmeggiani Francesco, Costagliola Ciro, Incorvaia Carlo, Sebastiani Adolfo, Gemmati Donato
Abstract excerpt
In Western Countries, the occurrence of choroidal neovascularization (CNV) secondary to different forms of macular degeneration represents a common cause of blindness. Particularly, age-related macular degeneration (AMD) and pathologic myopia (PM) are the most frequent diseases related to CNV development. At present, the combined employment of drugs acting against vascular endothelial growth factor (anti-VEGF)...
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