Predictive role of coagulation-balance gene polymorphisms in the efficacy of photodynamic therapy with verteporfin for classic choroidal neovascularization secondary to age-related macular degeneration.

doi:10.1097/FPC.0b013e3282f12a4e

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Article

Predictive role of coagulation-balance gene polymorphisms in the efficacy of photodynamic therapy with verteporfin for classic choroidal neovascularization secondary to age-related macular degeneration.

Pharmacogenetics and genomics - 1 Dec 2007

Parmeggiani Francesco, Costagliola Ciro, Gemmati Donato, D'Angelo Sergio, Perri Paolo, Scapoli Gian Luigi, Catozzi Linda, Federici Federica, Sebastiani Adolfo, Incorvaia Carlo

Abstract excerpt

OBJECTIVES: Age-related macular degeneration (AMD) represents the leading cause of blindness in Western populations. The majority of severe vision loss occurs in the exudative form of AMD, characterized by the development of choroidal neovascularization (CNV) beneath the fovea. Photodynamic therapy with verteporfin (PDT-V) represents one of the most largely employed modality that maybe achieves the subfoveal CNV...

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PMID: 18004208
DOI: 10.1097/FPC.0b013e3282f12a4e

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