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Article

Interactions of attenuated Mycobacterium tuberculosis phoP mutant with human macrophages.

PloS one - 24 Sept 2010

Ferrer Nadia L, Gomez Ana B, Neyrolles Olivier, Gicquel Brigitte, Martin Carlos

Abstract excerpt

BACKGROUND: Mycobacterium tuberculosis phoP mutant SO2 derived from a clinical isolate was shown to be attenuated in mouse bone marrow-derived macrophages and in vivo mouse infection model and has demonstrated a high potential as attenuated vaccine candidate against tuberculosis. METHODOLOGY/PRINCIPAL FINDINGS: In this study, we analyze the adhesion and the intracellular growth and trafficking of SO2 in human...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20885976
DOI: 10.1371/journal.pone.0012978
PMCID: PMC2945763

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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