Article
Caloric restriction delays aging-induced cellular phenotypes in rhesus monkey skeletal muscle.
Experimental gerontology - 1 Jan 2011
McKiernan Susan H, Colman Ricki J, Lopez Marisol, Beasley T Mark, Aiken Judd M, Anderson Rozalyn M, Weindruch Richard
Abstract excerpt
Sarcopenia is the age-related loss of skeletal muscle mass and function and is characterized by a reduction in muscle mass and fiber cross-sectional area, alterations in muscle fiber type and mitochondrial functional changes. In rhesus monkeys, calorie restriction (CR) without malnutrition improves survival and delays the onset of age-associated diseases and disorders including sarcopenia. We present a...
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