Article
Hepatitis B virus (HBV) subgenotypes C2 and B2 differ in lamivudine- and adefovir-resistance-associated mutational patterns in HBV-infected Chinese patients.
Journal of clinical microbiology - 1 Dec 2010
Li Xiaodong, Wang Lin, Zhong Yanwei, Wong Vincent Wai-Sun, Xu Zhihui, Liu Yan, Li Qinghong, Xin Shaojie, Zhao Jingmin, Xu Dongping
Abstract excerpt
We aimed to study the prevalence and clinical implications of hepatitis B virus (HBV) subgenotypes in Chinese patients. A total of 4,300 patients, mainly from northern China, were enrolled, including 182 patients with acute hepatitis B and 4,118 patients with chronic HBV infection who had been exposed to nucleoside or nucleotide analogs. HBV genotypes/subgenotypes were determined by direct sequencing of the HBV...
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