Dependence of acetazolamide teratogenesis on fetal and not maternal genotypes.

doi:10.1016/0890-6238(92)90022-l

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Article

Dependence of acetazolamide teratogenesis on fetal and not maternal genotypes.

Reproductive toxicology (Elmsford, N.Y.) - 1 Jan 1992

Beck S L, Manabat N

Abstract excerpt

This study assesses the relative contributions of dam and conceptus to sensitivity to acetazolamide teratogenesis in an in vivo mouse model. Reciprocal F1 outcrosses were made between mice resistant to the teratogenic effects of acetazolamide (SWV) and the susceptible C57BL/6JBk line. Female F1 p...

Topics

Abnormalities, Drug-Induced
Acetazolamide
Animals
Embryonic and Fetal Development
Female
Genotype
Male
Mice
Mice, Inbred C57BL
Mice, Inbred Strains
Pregnancy

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