Article
Biosynthesis and distribution of Lewis X- and Lewis Y-containing glycoproteins in the murine male reproductive system.
Glycobiology - 1 Feb 2011
Wang Chunmei, Huang Chengyang, Gu Yihua, Zhou Yuchuan, Zhu Zhengmei, Zhang Yonglian
Abstract excerpt
Although Lewis X (LeX) and Lewis Y (LeY) antigens were thought to play important roles in fertility, fucosyltransferase (Fut)-deficient (Fut1, Fut2 and Fut4) mice which lack LeX or LeY antigen are still fertile. In the present study, the Fut-deficient and wild-type mice were used to measure the expression of Fut mRNA along the mouse male reproductive tract and determine the role of each Fut in the biosynthesis of...
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