Article
Why Dom34 stimulates growth of cells with defects of 40S ribosomal subunit biosynthesis.
Molecular and cellular biology - 1 Dec 2010
Bhattacharya Arpita, McIntosh Kerri B, Willis Ian M, Warner Jonathan R
Abstract excerpt
A set of genome-wide screens for proteins whose absence exacerbates growth defects due to pseudo-haploinsufficiency of ribosomal proteins in Saccharomyces cerevisiae identified Dom34 as being particularly important for cell growth when there is a deficit of 40S ribosomal subunits. In contrast, strains with a deficit of 60S ribosomal proteins were largely insensitive to the loss of Dom34. The slow growth of cells...
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