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Article

Genome-block expression-assisted association studies discover malaria resistance genes in Anopheles gambiae.

Proceedings of the National Academy of Sciences of the United States of America - 17 Dec 2013

Li Jun, Wang Xiaohong, Zhang Genwei, Githure John I, Yan Guiyun, James Anthony A

Abstract excerpt

The malaria parasite-resistance island (PRI) of the African mosquito vector, Anopheles gambiae, was mapped to five genomic regions containing 80 genes, using coexpression patterns of genomic blocks. High-throughput sequencing identified 347 nonsynonymous single-nucleotide polymorphisms within these genes in mosquitoes from malaria-endemic areas in Kenya. Direct association studies between nonsynonymous...

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PMID: 24297936
DOI: 10.1073/pnas.1321024110
PMCID: PMC3870758

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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