Article
Danoprevir, an HCV NS3/4A protease inhibitor, improves insulin sensitivity in patients with genotype 1 chronic hepatitis C.
Gut - 1 Dec 2010
Moucari Rami, Forestier Nicole, Larrey Dominique, Guyader Dominique, Couzigou Patrice, Benhamou Yves, Voitot Hélène, Vidaud Michel, Seiwert Scott, Bradford Bill, Zeuzem Stefan, Marcellin Patrick
Abstract excerpt
BACKGROUND/AIM: Insulin resistance (IR) is a major predictor of treatment failure in patients with hepatitis C virus (HCV) infection treated with peginterferon/ribavirin. The aim of this study was to evaluate the short-term effect of an HCV protease inhibitor monotherapy on IR in parallel with an...
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