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Pneumocystis jirovecii Can Be Productively Cultured in Differentiated CuFi-8 Airway Cells

14 May 2014

Abstract excerpt

UNLABELLED: Although Pneumocystis jirovecii is a well-known and serious pathogen, all previous attempts to isolate, cultivate, and propagate this fungus have failed. This serious challenge in microbiology was addressed in the present study. We examined whether P. jirovecii could be cultured in a permanent three-dimensional air-liquid interface culture system formed by CuFi-8 cells, a differentiated...

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PMID: 24825015
DOI: 10.1128/mbio.01186-14

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