Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Variants in estrogen receptor alpha gene are associated with phenotypical expression of obsessive-compulsive disorder.

Psychoneuroendocrinology - 1 May 2011

Alonso P, Gratacòs M, Segalàs C, Escaramís G, Real E, Bayés M, Labad J, Pertusa A, Vallejo J, Estivill X, Menchón J M

Abstract excerpt

Compelling data from animal and clinical studies suggest that sex steroids may play a role in the etiopathology of obsessive-compulsive disorder (OCD). The aim of this study was to investigate whether variants in estrogen receptor genes ESR1 and ESR2 may contribute to the genetic susceptibility to OCD, through a case-control association study using an extensive linkage disequilibrium-mapping approach. Twenty tag...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Estrogen Receptor alpha

Share to Linkage Disequilibrium

Share to Obsessive-Compulsive Disorder

Share to Polymorphism, Single Nucleotide

Share to Young Adult

Source

Identifiers

PMID: 20850223
DOI: 10.1016/j.psyneuen.2010.07.022

Genes

ESR1
ESR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Variants in estrogen receptor alpha gene are associated with phenotypical expression of obsessive-compulsive disorder.PMID 20850223Read ↗

DNA Methylation at the Neonatal State and at the Time of Diagnosis: Preliminary Support for an Association with the Estrogen Receptor 1, Gamma-Aminobutyric Acid B Receptor 1, and Myelin Oligodendrocyte Glycoprotein in Female Adolescent Patients with OCDSemantic proximity Read ↗

Common variants of HTR3 genes are associated with obsessive-compulsive disorder and its phenotypic expression.Semantic proximity Read ↗

The need for inclusion of sex and age of onset variables in genetic association studies of obsessive-compulsive disorder: Overview.Semantic proximity Read ↗

Genetics of early-onset obsessive-compulsive disorder.Semantic proximity Read ↗

Sex differences in the genetic architecture of obsessive-compulsive disorderSemantic proximity Read ↗

Intronic SNP in ESR1 encoding human estrogen receptor alpha is associated with brain ESR1 mRNA isoform expression and behavioral traits.Semantic proximity Read ↗

Obsessive-compulsive disorder phenotypes: implications for genetic studies.Semantic proximity Read ↗

Corrigendum to "gender in obsessive-compulsive disorder: clinical and genetic findings" [Eur. Neuropsychopharmacol. 14 (2004) 105-113].Semantic proximity Read ↗

Role of GAD2 and HTR1B genes in early-onset obsessive-compulsive disorder: results from transmission disequilibrium study.Semantic proximity Read ↗

Selective alterations of endocannabinoid system genes expression in obsessive compulsive disorderSemantic proximity Read ↗

Correlations between single nucleotide polymorphisms in obsessive-compulsive disorder with the clinical features or response to therapy.Semantic proximity Read ↗

DNA variants affecting chromatin structure are key to the genetic architecture of obsessive compulsive disorder.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.