Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypic Plasticity of the Ovarian Surface Epithelium: TGF-β1 Induction of Epithelial to Mesenchymal Transition (EMT) in Vitro

15 Sept 2010

Abstract excerpt

Ovarian surface epithelium (OSE) is the most conceivable cell origin of epithelial ovarian carcinomas. Unlike many other epithelial tumors, the precancerous lesion acquires expression of epithelial markers, e.g. E-cadherin and claudins, suggesting that OSE cells undergo mesenchymal to epithelial transition (MET) during transformation. Recent findings indicate that TGF-β1, a prototypic stimulus of epithelial to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Kruppel-like factors research
Share to Wnt/β-catenin signaling in development and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20844000
DOI: 10.1210/en.2010-0486

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypic Plasticity of the Ovarian Surface Epithelium: TGF-β1 Induction of Epithelial to Mesenchymal Transition (EMT) in VitroPMID 20844000Read ↗

Phenotypic plasticity of neoplastic ovarian epithelium: unique cadherin profiles in tumor progression.Semantic proximity Read ↗

Epithelial–mesenchymal transition in ovarian cancerSemantic proximity Read ↗

The epithelial-mesenchymal transition and the estrogen-signaling in ovarian cancer.Semantic proximity Read ↗

Spontaneous malignant transformation of ovarian surface epithelial cells correlates with EMT alteration and stemness acquisitionSemantic proximity Read ↗

TGF-β: friend or foe? The role of TGF-β/SMAD signaling in epigenetic silencing of ovarian cancer and its implication in epigenetic therapySemantic proximity Read ↗

Molecular pathways regulating EGF-induced epithelio-mesenchymal transition in human ovarian surface epitheliumSemantic proximity Read ↗

Differences in expression patterns of the tight junction proteins,claudin 1, 3, 4 and 5, in human ovarian surface epithelium as compared to epithelia in inclusion cysts and epithelial ovarian tumours.Semantic proximity Read ↗

Characterization of cultured human ovarian surface epithelial cells: phenotypic plasticity and premalignant changes.Semantic proximity Read ↗

Induction by transforming growth factor-beta1 of epithelial to mesenchymal transition is a rare event in vitro.Semantic proximity Read ↗

An Ovol2-Zeb1 Mutual Inhibitory Circuit Governs Bidirectional and Multi-step Transition between Epithelial and Mesenchymal StatesSemantic proximity Read ↗

Smad7 maintains epithelial phenotype of ovarian cancer stem-like cells and supports tumor colonization by mesenchymal-epithelial transition.Semantic proximity Read ↗

Conditionally immortal ovarian cell lines for investigating the influence of ovarian stroma on the estrogen sensitivity and tumorigenicity of ovarian surface epithelial cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.