Article
Individualized treatment with combination of Peg-interferon alpha 2b and ribavirin in patients infected with HCV genotype 3.
Journal of hepatology - 1 Dec 2010
Mangia Alessandra, Bandiera Franco, Montalto Giuseppe, Mottola Leonardo, Piazzolla Valeria, Minerva Nicola, Pellicelli Adriano, Ricci Giovanni L, Cela Marina, Carretta Vito, Scotto Gaetano, Bacca Donato, Annicchiarico Brigida, Romano Mario, Russello Maurizio, Barbarini Giorgio, Agostinacchio Ernesto, Andriulli Angelo
Abstract excerpt
BACKGROUND & AIMS: The benefit of individualizing treatment for patients with genotype 3 HCV infection on the basis of viral clearance at week 4 (wk4-R) has not been firmly established. METHODS: Four hundred and fourteen patients received Peg-interferon alpha-2b plus 1000-1200 mg of ribavirin daily according with body weight > or <75 kg. Patients were randomized to standard 24 weeks (Std24) or to a 12 or 36 weeks...
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