Article
Reduced dose and duration of peginterferon alfa-2b and weight-based ribavirin in patients with genotype 2 and 3 chronic hepatitis C.
Journal of hepatology - 1 Sept 2011
Manns Michael, Zeuzem Stefan, Sood Ajit, Lurie Yoav, Cornberg Markus, Klinker Hartwig, Buggisch Peter, Rössle Martin, Hinrichsen Holger, Merican Ismail, Ilan Yaron, Mauss Stefan, Abu-Mouch Saif, Horban Andryes, Müller Thomas H, Welsch Christoph, Chen Rongdean, Faruqi Rab, Pedicone Lisa D, Wedemeyer Heiner
Abstract excerpt
BACKGROUND & AIMS: There is increasing interest in identifying patients with chronic hepatitis C genotype 2 or 3 infection in whom it is possible to lower the burden of therapy while retaining high levels of efficacy. METHODS: Treatment-naive patients with chronic hepatitis C genotype 2/3 infection were randomized to receive peginterferon alfa-2b (1.5μg/kg/wk) for 24weeks (group A); peginterferon alfa-2b...
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