Article
Improved responses to pegylated interferon alfa-2b and ribavirin by individualizing treatment for 24-72 weeks.
Gastroenterology - 1 Nov 2011
Sarrazin Christoph, Schwendy Susanne, Möller Bernd, Dikopoulos Nektarios, Buggisch Peter, Encke Jens, Teuber Gerlinde, Goeser Tobias, Thimme Robert, Klinker Hartwig, Boecher Wulf O, Schulte-Frohlinde Ewert, Prinzing Renate, Herrmann Eva, Zeuzem Stefan, Berg Thomas
Abstract excerpt
BACKGROUND & AIMS: Guidelines recommend that patients with chronic hepatitis C virus (HCV) infection be treated with pegylated interferon and ribavirin for 24, 48, or 72 weeks, based on their virologic response to treatment. We investigated the effects of treating patients for individualized durations. METHODS: We treated 398 treatment-naïve patients who had HCV genotype 1 infections with pegylated interferon...
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