Article
Genetic, nongenetic and epigenetic risk determinants in developmental programming of type 2 diabetes.
Acta obstetricia et gynecologica Scandinavica - 1 Nov 2014
Vaag Allan, Brøns Charlotte, Gillberg Linn, Hansen Ninna S, Hjort Line, Arora Geeti P, Thomas Nihal, Broholm Christa, Ribel-Madsen Rasmus, Grunnet Louise G
Abstract excerpt
Low birthweight (LBW) individuals and offspring of women with gestational diabetes mellitus (GDM) exhibit increased risk of developing type 2 diabetes (T2D) and associated cardiometabolic traits in adulthood, which for both groups may be mediated by adverse events and developmental changes in fetal life. T2D is a multifactorial disease occurring as a result of complicated interplay between genetic and both...
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