Article
Glucocerebrosidase is present in α-synuclein inclusions in Lewy body disorders.
Acta neuropathologica - 1 Nov 2010
Goker-Alpan Ozlem, Stubblefield Barbara K, Giasson Benoit I, Sidransky Ellen
Abstract excerpt
Mutations in the gene encoding the lysosomal enzyme glucocerebrosidase, known to cause Gaucher disease (GD), are a risk factor for the development of Parkinson disease (PD) and related disorders. This association is based on the concurrence of parkinsonism and GD, the identification of glucocereb...
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